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El aumento de la glucosa nos apunta hacia la diabetes, el aumento de la tensión arterial y aumento del colesterol. Muchas personas se hacen una analítica que les da unos datos normales, pero claro cuando se la hacen es cuando están fuera del ciclo de sustancias farmacológicas y lo regular es que en ese momento salga bien. Durante el ciclo se produce un aumento muy drástico del colesterol LDL, el malo, y una disminución muy acusada del colesterol HDL; el bueno. Esta alteración es tan notoria que, aunque el tiempo de uso sea de dieciséis semanas, es regular que acabe conllevando acumulación de placa arterial que, con el paso de los años, acaba siendo muy grande con los riesgos que esto conlleva, y aparecen las personas que sufren infartos o que tienen que implantarles un ‘stent’. Estas cosas en una persona de cincuenta años, obesa, que no hace deporte, que bebe y fuma te lo puedes esperar, pero cuando todo esto le ocurre a alguien de treinta años con un aspecto de deportista de élite, pues es más que preocupante.

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El origen de la contaminación se atribuye a empresas farmacéuticas chinas que comercializan AAS a granel. El 13,8% de las muestras analizadas en España estaban presentaban una contaminación cruzada de AAS que representaba el 6º puesto del ranking global (6). Son productos concebidos para cubrir las ingestas de macronutrientes en situaciones en las que no es posible ingerir comida real, como en las inmediaciones del ejercicio o durante el mismo. Como efecto asociado aparece la calvicie, que no se considera un efecto común, pero puede estar asociado con el uso de andrógenos, ya que éstos presentan un importante papel en el crecimiento del cabello36.

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Promueven el desarrollo del músculo esquelético (efecto anabólico) y en menor medida las características sexuales masculinas (efecto androgénico). No hay ninguno que carezca por completo de acción virilizante, por eso causa este efecto en las mujeres. Al aumentar la grasa subcutánea, los andrógenos pueden propiciar la producción de acné hasta en un 50% de consumidores.

  • En este sentido, los esteroides anabolizantes se utilizan en el contexto recreativo con el ánimo de aumentar la masa muscular, el rendimiento físico y también para mejorar la imagen.
  • En el trabajo de Pagonis et al.6, se llegó a la conclusión de que el consumo de agentes anabólicos, en personas gemelas, inducían a importantes cambios psiquiátricos en el consumidor de dichas sustancias.
  • Los comités olímpicos y paralímpicos de los distintos países y las federaciones deportivas han aceptado esta lista de prohibiciones.
  • Estudios recientes demuestran la afectación de las funciones ejecutivas en personas que abusan o dependen de los esteroides.

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Aunque la adicción a los esteroides no figura entre los trastornos relacionados con sustancias, aproximadamente el 30 por cien de los consumidores de anabolizantes desarrollan un cuadro comparable a otras adicciones. De hecho, la adicción a los anabolizantes está caracterizada por el consumo repetido a pesar de los efectos perjudiciales y la aparición del síndrome de abstinencia cuando se retiran. El problema surge cuando se utilizan fuera de sus indicaciones o con una finalidad distinta a la terapéutica. De hecho, un gran número de estudios indican alteraciones patológicas como consecuencia del uso indebido de anabolizantes, por ejemplo la adicción.

Como se ha observado en esta revisión se observó asociación entre la toma de agentes anabólicos y el aumento de la agresividad, la excitación, la irritabilidad…ya que la toma de estas sustancias se asocia con cambios de humor y un aumento de los episodios psicóticos33. En el estudio de Porcerelli y Sandler23, indicaban que los usuarios de EAA tendrían puntuaciones más altas para el narcisismo y puntuaciones más bajas para la empatía en comparación con el grupo que no consumía EAA. En este estudio se llega a la conclusión de que había una relación entre los EAA y personalidades narcisistas pero dejan constancia de la necesidad de más investigación para determinar una relación directa. En el trabajo de Pagonis et al.6, se llegó a la conclusión de que el consumo de agentes anabólicos, en personas gemelas, inducían a importantes cambios psiquiátricos en el consumidor de dichas sustancias. Otros efectos adversos que producen un aumento en el riesgo cardiovascular, es la disminución que los EAA producen sobre los niveles del colesterol-HDL acompañado de una elevación en los niveles del colesterol-LDL, lo que supone un perfil lipídico desfavorable19. Al riesgo cardiovascular que supone el uso de estas sustancias, hay que añadir que la toma de EAA 17 a-alquilado, los cuales presentan un grupo metilo en posición C-17, lo que hace posible la administración por vía oral, pudiendo estar asociado a la aparición de trombos32.

Encontrarte a chavales de veintipico años en diálisis por el uso de anabolizantes no deja de sorprender, y esto no se enseña en las redes sociales. Cuando les ocurre a estas personas simplemente se retiran y no quieren volver a saber nada de este mundillo nunca jamás o, en el peor de los casos, mueren por el camino. La androstendiona se produce en gónadas y suprarrenales a partir de dehidroepiandrosterona y es convertida a testosterona por la 17β-esteroid-deshidrogenasa. Ambos andrógenos elevan los niveles de testosterona e incrementan el cociente testosterona/epitestosterona, pudiendo detectarse también por espectofotometría de masas. El efecto sobre la fuerza muscular que producen las gonadotrofinas es escaso. La hormona luteinizante recombinante y hCG requieren una administración inyectable varias veces a la semana y son caras.

6-La creatina es una ayuda ergogénica muy utilizada en el mundo del deporte, sobre todo en ejercicios con un predominio del componente anaeróbico. Estudios más recientes apuntan que la creatina podría ser útil en distintas patologías, sobre todo enfermedades neurodegenerativas. Por otro lado se han descrito casos de creatina contaminada con MK (ostearina), un Modulador Selectivo de los Receptores de Andrógenos (SARM), incluido en la Lista de Sustancias Prohibidas. Geyer H et al publicaron en 2008 un estudio sobre una muestra de 634 DS orientados a la práctica deportiva, adquiridos en 13 países diferentes en 2001 y 2002. Un 15% de la muestra estaba contaminado con AAS (principalmente prohormonas).

Christian asegura que sabe más sobre el tema que cualquier médico, y que por ello asesora a sus clientes a través de un chat en su internet o del correo electrónico. “Tenemos incluso un turno de noche para cumplir con nuestros clientes europeos debido al cambio horario”, afirma el francés. Arnaud, por su lado, eligió un weblog para informarse sobre los peligros del dopaje y también consiguió información sobre la manera de hacerlo sin ayuda de nadie.

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